Nic Robinson

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

Qing Guo, Bryce L. Sopher, Katsutoshi Furukawa et al. · PubMed · 1997 · 482 citations

Life Sciences, Neurobiology, Neuroscience +17

Alzheimer’s Presenilin Mutation Sensitizes Neural Cells to Apoptosis Induced by Trophic Factor Withdrawal and Amyloid β-Peptide: Involvement of Calcium and Oxyradicals

Qing Guo, Bryce L. Sopher, Katsutoshi Furukawa et al. · Journal of Neuroscience · 1997 · 399 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Alzheimerʼs PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide

Qing Guo, Katsutoshi Furukawa, Bryce L. Sopher et al. · Neuroreport · 1996 · 320 citations

Life Sciences, Neurobiology, Neuroscience +17

Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: Reduced oxidative stress and preserved mitochondrial function

Qing Guo, Sylvia Christakos, Nic Robinson et al. · Proceedings of the National Academy of Sciences · 1998 · 219 citations

Life Sciences, Neurobiology, Neuroscience +17

Secreted β-Amyloid Precursor Protein Counteracts the Proapoptotic Action of Mutant Presenilin-1 by Activation of NF-κB and Stabilization of Calcium Homeostasis

Qing Guo, Nic Robinson, Mark P. Mattson · Journal of Biological Chemistry · 1998 · 194 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17