Youssif Budagaga

Sonidegib potentiates the cancer cells’ sensitivity to cytostatic agents by functional inhibition of ABCB1 and ABCG2 in vitro and ex vivo

Yu Zhang, Dimitrios Vagiannis, Youssif Budagaga et al. · Biochemical Pharmacology · 2022 · 16 citations

Medicine, Oncology, Pharmacology +11

Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo

Youssif Budagaga, Ziba Sabet, Yu Zhang et al. · Biochemical Pharmacology · 2023 · 15 citations

Medicine, Pharmacology, Pharmacotherapy +15

Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study

Ziba Sabet, Dimitrios Vagiannis, Youssif Budagaga et al. · International Journal of Molecular Sciences · 2022 · 14 citations · Full text

Medicine, Oncology, Pharmacology +17

Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter

Dimitrios Vagiannis, Yu Zhang, Youssif Budagaga et al. · Toxicology and Applied Pharmacology · 2021 · 11 citations

Medicine, Pharmacokinetics, Pharmacology +16

Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters

A Morell, Youssif Budagaga, Dimitrios Vagiannis et al. · Archives of Toxicology · 2022 · 11 citations

Life Sciences, Medicinal Chemistry, Pharmacology +15