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Dimitrios Vagiannis

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Publications

11

Citations

210

H-Index

10

Active since

2019

Affiliations

Charles University(Current)

University of Hradec Králové

Brandenburg University of Technology Cottbus-Senftenberg

National Center for Toxicological Research

United States Food and Drug Administration

Dimitrios Vagiannis is an author at Charles University specializing in medicine, pharmacology, and drug resistance.

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Top concepts

Publications per year

2019–2022

11

Publications

11

Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance

Jakub Hofman, Dimitrios Vagiannis, Si Chen et al. · Chemico-Biological Interactions · 2021 · 39 citations

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Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes

Jakub Hofman, Aleš Šorf, Dimitrios Vagiannis et al. · Molecular Pharmaceutics · 2019 · 28 citations

Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme

Dimitrios Vagiannis, Eva Novotná, Adam Skarka et al. · Cancers · 2020 · 23 citations · Full text

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance

Jakub Hofman, Aleš Šorf, Dimitrios Vagiannis et al. · Drug Metabolism and Disposition · 2019 · 22 citations · Full text

Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme

Dimitrios Vagiannis, Yu Zhang, Eva Novotná et al. · Biochemical Pharmacology · 2020 · 19 citations

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