Dimitrios Vagiannis

Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance

Jakub Hofman, Dimitrios Vagiannis, Si Chen et al. · Chemico-Biological Interactions · 2021 · 43 citations

Medicine, Pharmacokinetics, Pharmacology +14

Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes

Jakub Hofman, Aleš Šorf, Dimitrios Vagiannis et al. · Molecular Pharmaceutics · 2019 · 28 citations

Medicine, Oncology, Pharmacology +17

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance

Jakub Hofman, Ales Sorf, Dimitrios Vagiannis et al. · Drug Metabolism and Disposition · 2019 · 23 citations · Full text

Medicine, Oncology, Pharmacology +17

Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme

Dimitrios Vagiannis, Eva Novotná, Adam Skarka et al. · Cancers · 2020 · 23 citations · Full text

Medicine, Oncology, Pharmacology +17

Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme

Dimitrios Vagiannis, Yu Zhang, Eva Novotná et al. · Biochemical Pharmacology · 2020 · 19 citations

Medicine, Pharmacokinetics, Pharmacology +16