Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators

Nicola K. Wilson, Samuel D. Foster, Xiaonan Wang, +10

Cell stem cell

Transcriptional RegulationCell LineageDevelopmental BiologyBlood Stem/progenitor CellsMedicine +11

Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis

Victoria Moignard, Iain C. Macaulay, Gemma Swiers, +10

Nature Cell Biology

Progenitor CellsTranscriptional NetworksFunctional GenomicsSingle Cell SequencingMedicine +13

Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner

Yahya Al-Matary, Lacramioara Botezatu, Bertram Opalka, +10

Haematologica

Hematological MalignancyCell DivisionMacrophage PolarizationAcute Myeloid LeukemiaMixed-phenotype Acute Leukemia +11

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

Dominik Beck, Julie A.I. Thoms, D. S. Perera, +9

Blood

Identification of Functional Networks of Estrogen- and c-Myc-Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer

Elizabeth A. Musgrove, C. Marcelo Sergio, Sherene Loi, +11

PLoS ONE

Hard-wired heterogeneity in blood stem cells revealed using a dynamic regulatory network model

Nicola Bonzanni, Abhishek D. Garg, K. Anton Feenstra, +6

Bioinformatics

Twelve versus 36 months of adjuvant imatinib (IM) as treatment of operable GIST with a high risk of recurrence: Final results of a randomized trial (SSGXVIII/AIO).

Heikki Joensuu, Mikael Eriksson, J. Hatrmann, +16

Journal of Clinical Oncology

Surgical OncologyCancer ManagementImmunologyPathologyAnnual Meeting Proceedings +14

Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia

Cyrus Khandanpour, James D. Phelan, Judith Schütte, +9

Cancer Cell

Tumor BiologyGenome InstabilityChromatinMedicineMixed-phenotype Acute Leukemia +6

Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-Myc

C. Elizabeth Caldon, C. Marcelo Sergio, Judith Schütte, +4

Molecular and Cellular Biology

An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability

Judith Schütte, Huange Wang, Stella Antoniou, +14

eLife

Gene Regulatory NetworkGene Expression ProfilingCellular PhysiologyKey Hspc RegulatorsTranscriptional Regulation +21