Giselle R. Wiggin

MSK2 and MSK1 mediate the mitogen‐ and stress‐induced phosphorylation of histone H3 and HMG‐14

Ana Soloaga, Stuart Thomson, Giselle R. Wiggin et al. · The EMBO Journal · 2003 · 498 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

MSK1 and MSK2 Are Required for the Mitogen- and Stress-Induced Phosphorylation of CREB and ATF1 in Fibroblasts

Giselle R. Wiggin, Ana Soloaga, Julia M. Foster et al. · Molecular and Cellular Biology · 2002 · 447 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

A.S. Dore, Krzysztof Okrasa, Jayesh C. Patel et al. · Nature · 2014 · 411 citations

Life Sciences, Molecular Biology, Neuroscience +12

Structural insight into allosteric modulation of protease-activated receptor 2

R.K. Cheng, Cédric Fiez-Vandal, Oliver Schlenker et al. · Nature · 2017 · 253 citations

Life Sciences, Biochemistry, Molecular Biology +16

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu ₅ Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile)

J.A. Christopher, Sarah J. Aves, K.A. Bennett et al. · Journal of Medicinal Chemistry · 2015 · 159 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17