Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

Tania Løve Aaes, Agnieszka Kaczmarek, Tinneke Delvaeye, +16

Cell Reports

The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation Program

Bram De Craene, Barbara Gilbert, Christophe P. Stove, +3

Cancer Research

Snail promotes Wnt target gene expression and interacts with β-catenin

Volker Stemmer, Bram De Craene, Geert Berx, +1

Oncogene

Transcriptional RegulationDevelopmental BiologySignaling PathwayMolecular RegulationGene Regulation +5

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

Geertrui Denecker, Niels Vandamme, Özden Akay, +19

Cell Death and Differentiation

Transcriptional RegulationSignaling PathwayZeb2-mitf-zeb1 Transcriptional NetworkMelanomaCancer Genomics +7

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

Omar Nyabi, Michael Naessens, Katharina Haigh, +15

Nucleic Acids Research

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential

Bram De Craene, Geertrui Denecker, Petra Vermassen, +6

Cell Death and Differentiation

Enhanced CytoprotectionCutaneous BiologyCancer InitiationMetastatic PotentialDermatology +6

A novel RIPK4–IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

Philippe De Groote, Hong Thi Tran, Mathias Fransen, +14

Cell Death and Differentiation

Popliteal Pterygium SyndromesEpithelial FusionsSignal TransductionSignaling PathwayReceptor Tyrosine Kinase +6

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells

Elly De Vlieghere, Félix Gremonprez, Laurine Verset, +12

Biomaterials

Tumor-environment BiomimeticsPeritoneal Metastasis FormationMedicineBiological MicroenvironmentsCancer Biology +9

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection

Tania Løve Aaes, Hanne Verschuere, Agnieszka Kaczmarek, +12

The Journal of Immunology

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

Marianthi Tatari, Bram De Craene, Bieke Soen, +9

Cellular and Molecular Life Sciences

Skin DevelopmentDevelopmental BiologySignal TransductionZeb2-transgene ExpressionNatural Sciences +8