Penelope J. Cross

Tyrosine Latching of a Regulatory Gate Affords Allosteric Control of Aromatic Amino Acid Biosynthesis

Penelope J. Cross, Renwick C. J. Dobson, Mark L. Patchett et al. · Journal of Biological Chemistry · 2011 · 62 citations · Full text

Molecular Biology, Peptide Science, Chemical Biology +17

Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain

Penelope J. Cross, Timothy M. Allison, Renwick C. J. Dobson et al. · Proceedings of the National Academy of Sciences · 2013 · 52 citations · Full text

Regulatory Domain, Modular Allostery, Engineering +21

First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer

Emilia Arturo, Kushol Gupta, A. Héroux et al. · Proceedings of the National Academy of Sciences · 2016 · 52 citations · Full text

Protein Chemistry, Autoinhibited Tetramer, å Crystal Structure +15

Dynamic Cross-Talk among Remote Binding Sites: The Molecular Basis for Unusual Synergistic Allostery

Wanting Jiao, Richard D. Hutton, Penelope J. Cross et al. · Journal of Molecular Biology · 2011 · 46 citations

Dynamic Cross-talk, Systems Biology, Signal Transduction +11

Exploring modular allostery via interchangeable regulatory domains

Yifei Fan, Penelope J. Cross, Geoffrey B. Jameson et al. · Proceedings of the National Academy of Sciences · 2018 · 32 citations · Full text