The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody

Don M. Benson, Courtney E. Bakan, Anjali Mishra, +14

Blood

Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes

Jason A. Dubovsky, Kyle A. Beckwith, Gayathri Natarajan, +26

Blood

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

Yusuke Shiozawa, Elisabeth A. Pedersen, Aaron M. Havens, +14

Journal of Clinical Investigation

Adult Stem CellCancer BiologyTumor BiologyMouse Bone MarrowHuman Prostate Cancer +14

Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis

Younghun Jung, Jin Koo Kim, Yusuke Shiozawa, +15

Nature Communications

Regenerative MedicineMesenchymal Stem CellsMedicineStem Cell ResearchEpithelial-mesenchymal Interactions +8

Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia

Shujun Liu, Lai‐Chu Wu, Jiuxia Pang, +24

Cancer Cell

Hematological MalignancySp1/nfκb/hdac/mir-29b Regulatory NetworkMedicineCell BiologyTumor Biology +1

Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling

Georg Feldmann, Anjali Mishra, Seung‐Mo Hong, +6

Cancer Research

Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation

Anjali Mishra, Shujun Liu, Gregory H. Sams, +23

Cancer Cell

Hematological MalignancyChromatinAberrant OverexpressionChromosomal InstabilityMixed-phenotype Acute Leukemia +8

Erythropoietin mediated bone formation is regulated by mTOR signaling

Jinkoo Kim, Younghun Jung, Hongli Sun, +6

Journal of Cellular Biochemistry

Regenerative MedicineSclerostinSignal TransductionBone Morphogenic ProteinMtor Inhibition +11

TBK1 Regulates Prostate Cancer Dormancy through mTOR Inhibition

Jin Koo Kim, Younghun Jung, Jingcheng Wang, +7

Neoplasia

Inhibition of the receptor tyrosine kinase Axl impedes activation of the FLT3 internal tandem duplication in human acute myeloid leukemia: implications for Axl as a potential therapeutic target

Il‐Kyoo Park, Anjali Mishra, Jason C. Chandler, +3

Blood