The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

Paolo Neviani, Ramasamy Santhanam, Rossana Trotta, +14

Cancer Cell

Cell RegulationBlast Crisis CmlCell SignalingMedicineTumor Suppressor +8

Clinical response and <i>miR-29b</i> predictive significance in older AML patients treated with a 10-day schedule of decitabine

William Blum, Ramiro Garzon, Rebecca B. Klisovic, +19

Proceedings of the National Academy of Sciences

FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia

Paolo Neviani, Ramasamy Santhanam, Joshua J. Oaks, +17

Journal of Clinical Investigation

Phase I Study of Decitabine Alone or in Combination With Valproic Acid in Acute Myeloid Leukemia

William Blum, Rebecca B. Klisovic, Bjoern Hackanson, +15

Journal of Clinical Oncology

Pro- and Antiinflammatory Cytokine Signaling: Reciprocal Antagonism Regulates Interferon-gamma Production by Human Natural Killer Cells

Jianhua Yu, Wei Min, Brian Becknell, +15

Immunity

InflammationCytokineInterferon-gamma ProductionAutoimmune DiseaseInnate Immune System +10

A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors

Fei Yan, Aref Al‐Kali, Zijie Zhang, +6

Cell Research

Sodium channels contribute to microglia/macrophage activation and function in EAE and MS

Matthew Craner, Tina G. Damarjian, Shujun Liu, +6

Glia

InflammationSodium Channel BlockersNeurophysiologyMedicineImmunology +12

Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia

Shujun Liu, Lai‐Chu Wu, Jiuxia Pang, +24

Cancer Cell

Hematological MalignancySp1/nfκb/hdac/mir-29b Regulatory NetworkMedicineCell BiologyTumor Biology +1

Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation

Anjali Mishra, Shujun Liu, Gregory H. Sams, +23

Cancer Cell

Hematological MalignancyChromatinAberrant OverexpressionChromosomal InstabilityMixed-phenotype Acute Leukemia +8

Expression of Adipocyte/Macrophage Fatty Acid–Binding Protein in Tumor-Associated Macrophages Promotes Breast Cancer Progression

Jiaqing Hao, Fei Yan, Yuwen Zhang, +14

Cancer Research