Salim Bouchène

Utility of In Vitro Systems and Preclinical Data for the Prediction of Human Intestinal First-Pass Metabolism during Drug Discovery and Preclinical Development

Fredrik Karlsson, Salim Bouchène, Constanze Hilgendorf et al. · Drug Metabolism and Disposition · 2013 · 45 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Pharmacokinetics of Colistin Methansulphonate (CMS) and Colistin after CMS Nebulisation in Baboon Monkeys

Sandrine Marchand, Salim Bouchène, M. De Monte et al. · Pharmaceutical Research · 2015 · 21 citations

Medicine, Pharmacokinetics, Pharmacology +11

A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6

Anders Thorsted, Salim Bouchène, Eva Tano et al. · PLoS ONE · 2019 · 20 citations · Full text

Life Sciences, Immunology, Pharmacokinetics +15

A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion

Alexis Viel, Jérôme Henri, Salim Bouchène et al. · Pharmaceutical Research · 2018 · 14 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Model‐based prediction of effective target exposure for <scp>MEN1611</scp> in combination with trastuzumab in <scp>HER2</scp>‐positive advanced or metastatic breast cancer patients

Elena M. Tosca, Elisa Borella, Chiara Piana et al. · CPT Pharmacometrics & Systems Pharmacology · 2023 · 14 citations · Full text

Medicine, Oncology, Pharmacology +17