William Crumb

An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

William Crumb, José Vicente, Lars Johannesen et al. · Journal of Pharmacological and Toxicological Methods · 2016 · 286 citations · Full text

Vitro Proarrhythmia Assay, Cardiac Muscle, Heart Failure +14

Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias

Ksenia Blinova, Jayna Stohlman, José Vicente et al. · Toxicological Sciences · 2016 · 271 citations

Cardiac Muscle, Translational Medicine, Heart Failure +15

Three-Dimensional Quantitative Structure-Activity Relationship for Inhibition of Human Ether-a-Go-Go-Related Gene Potassium Channel

Sean Ekins, William Crumb, R. Dustan Sarazan et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 257 citations

A Novel, Potent, and Selective Inhibitor of Cardiac Late Sodium Current Suppresses Experimental Arrhythmias

Luiz Belardinelli, Gongxin Liu, Cathy Smith-Maxwell et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 189 citations

Assessment of an <i>In Silico</i> Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci<scp>PA</scp> Initiative

Zhihua Li, Bradley J. Ridder, Xiaomei Han et al. · Clinical Pharmacology & Therapeutics · 2018 · 166 citations · Full text