William Crumb

An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

William Crumb, José Vicente, Lars Johannesen et al. · Journal of Pharmacological and Toxicological Methods · 2016 · 296 citations · Full text

Medicine, Cardiology, Pharmacology +13

Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias

Ksenia Blinova, Jayna Stohlman, José Vicente et al. · Toxicological Sciences · 2016 · 277 citations

Medicine, Cardiology, Pharmacology +13

Three-Dimensional Quantitative Structure-Activity Relationship for Inhibition of Human Ether-a-Go-Go-Related Gene Potassium Channel

Sean Ekins, William Crumb, R. Dustan Sarazan et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 261 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

A Novel, Potent, and Selective Inhibitor of Cardiac Late Sodium Current Suppresses Experimental Arrhythmias

Luiz Belardinelli, Gongxin Liu, Cathy Smith-Maxwell et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 190 citations

Medicine, Cardiology, Pharmacology +17

Assessment of an <i>In Silico</i> Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci<scp>PA</scp> Initiative

Zhihua Li, Bradley J. Ridder, Xiaomei Han et al. · Clinical Pharmacology & Therapeutics · 2018 · 179 citations · Full text

Medicine, Cardiology, Pharmacology +12