Hiroshi Inakura

The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura et al. · Biomaterials · 2010 · 149 citations

Inflammation, Engineering, Surface Functionalization +8

Suppression of nanosilica particle-induced inflammation by surface modification of the particles

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura et al. · Archives of Toxicology · 2012 · 53 citations

Nanoparticles, Nanomedicine, Engineering +9

Cytotoxicity of amorphous silica particles against macrophage-like THP-1 cells depends on particle-size and surface properties.

Tomohiro Morishige, Yayoi Yoshioka, Hiroshi Inakura et al. · PubMed · 2010 · 24 citations

Engineering, Immunotoxicology, Immunology +17

Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura et al. · Biomaterials · 2010 · 16 citations

Light Mutant, Cancer Therapy, Signal Transduction +12

Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura et al. · Biochemical and Biophysical Research Communications · 2010 · 12 citations

Photoreceptor Cell, Signal Transduction, Biochemistry +11