Tomohiro Morishige

The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura et al. · Biomaterials · 2010 · 149 citations

Inflammation, Engineering, Surface Functionalization +8

Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration

Jianqing Gao, Yusuke Eto, Yasuo Yoshioka et al. · Journal of Controlled Release · 2007 · 99 citations

Effective Tumor, Immunology, Systemic Administration +7

Titanium dioxide induces different levels of IL-1β production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B

Tomohiro Morishige, Yasuo Yoshioka, Aya Tanabe et al. · Biochemical and Biophysical Research Communications · 2010 · 93 citations

Inflammation, Cytokine, Signal Transduction +14

Suppression of nanosilica particle-induced inflammation by surface modification of the particles

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura et al. · Archives of Toxicology · 2012 · 53 citations

Nanoparticles, Nanomedicine, Engineering +9

Systemic administration of a PEGylated adenovirus vector with a cancer-specific promoter is effective in a mouse model of metastasis

Xingang Yao, Yasuo Yoshioka, Tomohiro Morishige et al. · Gene Therapy · 2009 · 48 citations

Tumor Biology, Medicine, Systemic Administration +8