Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry (BSAR)

Florence Schleich, Guy Brusselle, Renaud Louis, +6

Respiratory Medicine

AsthmaEpidemiologyAllergyGenetic EpidemiologyClinical Epidemiology +5

Sublingual grass pollen immunotherapy is associated with increases in sublingual Foxp3‐expressing cells and elevated allergen‐specific immunoglobulin G4, immunoglobulin A and serum inhibitory activity for immunoglobulin E‐facilitated allergen binding to B cells

Guy W. Scadding, Mohamed H. Shamji, Mikila R. Jacobson, +7

Clinical & Experimental Allergy

Grass Pollen Immunotherapy Induces an Allergen-Specific IgA2 Antibody Response Associated with Mucosal TGF-β Expression

Charles Pilette, Kayhan T. Nouri‐Aria, Mikila R. Jacobson, +4

The Journal of Immunology

SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule

Alexis Wérion, Leïla Belkhir, Marie Perrot, +53

Kidney International

GlomerulonephritisUrologyRenal FunctionMedicineKidney Failure +8

“Real-life” effectiveness of omalizumab in patients with severe persistent allergic asthma: The PERSIST study

Guy Brusselle, Alain Michils, Renaud Louis, +12

Respiratory Medicine

AsthmaAllergyAllergy MedicineAllergenPersist Study +2

Reduced Epithelial Expression of Secretory Component in Small Airways Correlates with Airflow Obstruction in Chronic Obstructive Pulmonary Disease

Charles Pilette, Véronique Godding, Róbert Kiss, +7

American Journal of Respiratory and Critical Care Medicine

InflammationAsthmaSecretory ComponentSevere CopdAllergy +11

Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition

Sophie Gohy, Cloé Hupin, Chantal Fregimilicka, +10

European Respiratory Journal

Advanced Lung DiseaseLung InflammationCopd Airway EpitheliumVimentin ExpressionMesenchymal Transition +15

LPS induces IL-10 production by human alveolar macrophages via MAPKinases- and Sp1-dependent mechanisms

Hugues Chanteux, A. Guisset, Charles Pilette, +1

Respiratory Research

CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge

Charles Pilette, James N. Francis, Stephen J. Till, +1

European Respiratory Journal

β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination

R. De Smet, Tine Demoor, Stéphanie Verschuere, +8

Journal of Controlled Release

VaccinologyVaccinationMucosal VaccinationMucosal Antigen DeliveryVaccine Development +5