Julian C.‐H. Chen

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

Julian C.‐H. Chen, J. Krucinski, Larry J. W. Miercke et al. · Proceedings of the National Academy of Sciences · 2000 · 400 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

Shiou‐Chuan Tsai, Larry J. W. Miercke, J. Krucinski et al. · Proceedings of the National Academy of Sciences · 2001 · 214 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90

Joseph M. Jez, Julian C.‐H. Chen, Giulio Rastelli et al. · Chemistry & Biology · 2003 · 197 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Structure of Bovine Pancreatic Cholesterol Esterase at 1.6 Å:  Novel Structural Features Involved in Lipase Activation^,

Julian C.‐H. Chen, Larry J. W. Miercke, J. Krucinski et al. · Biochemistry · 1998 · 104 citations

Life Sciences, Biochemistry, Molecular Biology +15

Binding of a Designed Substrate Analogue to Diisopropyl Fluorophosphatase:  Implications for the Phosphotriesterase Mechanism

Marc‐Michael Blum, Frank Löhr, André Richardt et al. · Journal of the American Chemical Society · 2006 · 95 citations

Life Sciences, Biochemistry, Molecular Biology +12