Julie Ducharme

IN VITRO METABOLISM OF CHLOROQUINE: IDENTIFICATION OF CYP2C8, CYP3A4, AND CYP2D6 AS THE MAIN ISOFORMS CATALYZING N-DESETHYLCHLOROQUINE FORMATION

Denis Projean, Bruno Baune, Robert Farinotti et al. · Drug Metabolism and Disposition · 2003 · 183 citations

New Diarylmethylpiperazines as Potent and Selective Nonpeptidic δ Opioid Receptor Agonists with Increased In Vitro Metabolic Stability

Niklas Plobeck, Daniel Delorme, Zhongyong Wei et al. · Journal of Medicinal Chemistry · 2000 · 115 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +15

Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N -demethylation in human liver microsomes

Denis Projean, Pierre-Emmanuel Morin, Tao Tu et al. · Xenobiotica · 2003 · 97 citations

Major Cytochrome P450, Molecular Biology, Pharmacotherapy +18

Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats

Eric Grazzini, Carole Puma, Marie‐Odile Roy et al. · Proceedings of the National Academy of Sciences · 2004 · 96 citations · Full text

<i>N,N</i>-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide:  A Novel, Exceptionally Selective, Potent δ Opioid Receptor Agonist with Oral Bioavailability and Its Analogues

Zhongyong Wei, W. A. Brown, Bryan K. Takasaki et al. · Journal of Medicinal Chemistry · 2000 · 81 citations · Full text

Oral Bioavailability, Pharmacotherapy, Experimental Pharmacology +18