Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

Gi-Bang Koo, Michael K. Morgan, Da‐Gyum Lee, +19

Cell Research

Rip3 ExpressionOncologyMethylation-dependent LossOncogenic AgentMedicine +7

HS-173, a Novel PI3K Inhibitor, Attenuates the Activation of Hepatic Stellate Cells in Liver Fibrosis

Mi Kwon Son, Ye-Lim Ryu, Kyung Hee Jung, +8

Scientific Reports

Liver FibrosisNovel Imidazopyridine AnalogueHepatic Stellate CellsApoptosisImmunology +24

Oncolytic adenovirus expressing relaxin (YDC002) enhances therapeutic efficacy of gemcitabine against pancreatic cancer

Kyung Hee Jung, Il-Kyu Choi, Hee‐Seung Lee, +6

Cancer Letters

Tumor BiologyOncologyPancreatic CancerMedicineTherapeutic Efficacy +7

SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway

Mi Kwon Son, Kyung Hee Jung, Sang‐Won Hong

Food Chemistry

Pulsatilla Saponin DSignaling PathwayInduces ApoptosisApoptosisCell Death +6

Tumor vessel normalization by the PI3K inhibitor HS-173 enhances drug delivery

Soo Jung Kim, Kyung Hee Jung, Mi Kwon Son, +7

Cancer Letters

MedicinePi3k Inhibitor Hs-173PharmacologyTumor Vessel NormalizationTumor Targeting +8

A novel imidazopyridine PI3K inhibitor with anticancer activity in non-small cell lung cancer cells

Hyunseung Lee, Soo Jung Kim, Kyung Hee Jung, +4

Oncology Reports

ANGPTL4 accelerates KRASG12D-Induced acinar to ductal metaplasia and pancreatic carcinogenesis

Hong Yan, Kyung Hee Jung, Ji Eun Lee, +7

Cancer Letters

Krasg12d-induced AcinarCancer ResearchSignaling PathwayPancreatic CancerMedicine +7

Therapeutic effect of human clonal bone marrow-derived mesenchymal stem cells in severe acute pancreatitis

Kyung Hee Jung, TacGhee Yi, Mi Kwon Son, +2

Archives of Pharmacal Research

Regenerative MedicineSevere Acute PancreatitisTherapeutic EffectMedicineAdult Stem Cell +8

KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer

Yeo Wool Kang, Ji Eun Lee, Kyung Hee Jung, +12

Cancer Letters

Pancreatic CancerMedicineImmunologyAnti-cancer ActivityImmune Checkpoint Inhibitor +8

HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer

Marufa Rumman, Kyung Hee Jung, Zhenghuan Fang, +8

Oncotarget

Tumor BiologyPancreatic CancerNovel Pi3k InhibitorMedicineTumor Growth +10