Concepedia
Author
Morgan Yapundich
Also Known As
14
Publications
343
Citations
9
H-Index
0
Concepts
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All Concepts
8
288
BCL11A enhancer–edited hematopoietic stem cells persist in rhesus monkeys without toxicity
Selami Demirci, Jing Zeng, Yuxuan Wu, +24
Journal of Clinical Investigation
2020
66
Cas9 protein delivery non-integrating lentiviral vectors for gene correction in sickle cell disease
Naoya Uchida, Claire Drysdale, Tina Nassehi, +9
Molecular Therapy — Methods & Clinical Development
2021
50
High-Efficiency Lentiviral Transduction of Human CD34+ Cells in High-Density Culture with Poloxamer and Prostaglandin E2
Naoya Uchida, Tina Nassehi, Claire Drysdale, +7
2019
45
Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model
Naoya Uchida, Tina Nassehi, Claire Drysdale, +10
Molecular Therapy
36
Low-Dose Busulfan Reduces Human CD34+ Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice
Alexis Leonard, Morgan Yapundich, Tina Nassehi, +7
28
Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models
Naoya Uchida, Linhong Li, Tina Nassehi, +15
Cell Reports Medicine
27
βT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells
Selami Demirci, Bjorg Gudmundsdottir, Quan Li, +8
22
Sustained fetal hemoglobin induction in vivo is achieved by <i>BCL11A</i> interference and coexpressed truncated erythropoietin receptor
Naoya Uchida, Francesca Ferrara, Claire Drysdale, +17
Science Translational Medicine
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