Kenichiro Shimokawa

In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)

Nobumichi Ohoka, Keiichiro Okuhira, Masahiro Ito et al. · Journal of Biological Chemistry · 2017 · 237 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation

Kenichiro Shimokawa, Norihito Shibata, Tomoya Sameshima et al. · ACS Medicinal Chemistry Letters · 2017 · 103 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation

Nobumichi Ohoka, Yoko Morita, Katsunori Nagai et al. · Journal of Biological Chemistry · 2018 · 103 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Development of protein degradation inducers of oncogenic <scp>BCR</scp>‐<scp>ABL</scp> protein by conjugation of <scp>ABL</scp> kinase inhibitors and <scp>IAP</scp> ligands

Norihito Shibata, Naoki Miyamoto, Katsunori Nagai et al. · Cancer Science · 2017 · 99 citations · Full text

Medicine, Molecular Biology, Oncology +15

Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER)

Nobumichi Ohoka, Osamu Ujikawa, Kenichiro Shimokawa et al. · Chemical and Pharmaceutical Bulletin · 2018 · 54 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17