Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

Hongfang Wang, James Zou, Bo Zhao, +10

Proceedings of the National Academy of Sciences

MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma

Adlai R. Grayson, Erica M. Walsh, Michael J. Cameron, +10

Oncogene

Nut Midline CarcinomaTumor BiologyOncologyOncogenic AgentMedicine +6

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

Michael Kluk, Todd Ashworth, Hongfang Wang, +27

PLoS ONE

Hematological MalignancyLymphoid NeoplasiaOncologyMedicineMalignant Blood Disorder +12

Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2

Wendy R. Gordon, Didem Vardar‐Ulu, Sarah L’Heureux, +8

PLoS ONE

Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL

Jessica Tatarek, Kathleen Cullion, Todd Ashworth, +3

Blood

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

Todd Ashworth, Warren S. Pear, Mark Y. Chiang, +7

Blood

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

Robin Jeannet, Jérôme Mastio, Alejandra Macias-Garcia, +12

Blood

Opposing Functions of TFII-I Spliced Isoforms in Growth Factor-Induced Gene Expression

Shweta Hakre, Marı́a Isabel Tussié-Luna, Todd Ashworth, +4

Molecular Cell

Transcriptional RegulationSystems BiologyDevelopmental BiologySignal TransductionTfii-i Spliced Isoforms +10

Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I

Rodrigo Peña‐Hernández, Maud Marques, Khalid Hilmi, +8

Proceedings of the National Academy of Sciences

Calponin is required for agonist‐induced signal transduction ‐ evidence from an antisense approach in ferret smooth muscle

Hyun‐Dong Je, Samudra S. Gangopadhyay, Todd Ashworth, +1

The Journal of Physiology

Muscle FunctionExperimental BiologyFerret AortaCytoskeletonMechanotransduction +20