Pin Wan

SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

Pan Pan, Miaomiao Shen, Zhenyang Yu et al. · Nature Communications · 2021 · 489 citations · Full text

STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection

Wenbiao Wang, Dingwen Hu, Caifeng Wu et al. · PLoS Pathogens · 2020 · 221 citations · Full text

Innate Immune System, Viral Pathogenesis, Immunology +24

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

Pan Pan, Geng Li, Miaomiao Shen et al. · PLoS Pathogens · 2021 · 80 citations · Full text

Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome

Wenbiao Wang, Dingwen Hu, Yuqian Feng et al. · BMC Biology · 2020 · 79 citations · Full text

Cullin1 binds and promotes NLRP3 ubiquitination to repress systematic inflammasome activation

Pin Wan, Qí Zhāng, Weiyong Liu et al. · The FASEB Journal · 2019 · 76 citations

Immunology, Cell Death, Inflammation +20