Helga Hofmann-Sieber

Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity

Janet Karpinski, Ilona Hauber, Jan Chemnitz et al. · Nature Biotechnology · 2016 · 122 citations

Life Sciences, Genetics, Molecular Biology +15

Highly Significant Antiviral Activity of HIV-1 LTR-Specific Tre-Recombinase in Humanized Mice

Ilona Hauber, Helga Hofmann-Sieber, Jan Chemnitz et al. · PLoS Pathogens · 2013 · 61 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach

Josephine Abi‐Ghanem, Janet Chusainow, Madina Karimova et al. · Nucleic Acids Research · 2012 · 34 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16

Evidence That the Adenovirus Single-Stranded DNA Binding Protein Mediates the Assembly of Biomolecular Condensates to Form Viral Replication Compartments

Paloma Hidalgo, Diana Mojica-Santamaría, Konstantin von Stromberg et al. · Viruses · 2021 · 33 citations · Full text

Life Sciences, Biology, Biophysics +17

Excision of HIV-1 Proviral DNA by Recombinant Cell Permeable Tre-Recombinase

Poornima Priyadarshini, Helga Hofmann-Sieber, Marcel Krepstakies et al. · PLoS ONE · 2012 · 27 citations · Full text

Medicine, Infectious Diseases, Molecular Biology +17