Philip G. Griffiths

A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy

Thomas Klopstock, Patrick Yu‐Wai‐Man, Konstantinos Dimitriadis et al. · Brain · 2011 · 533 citations · Full text

Multi-system neurological disease is common in patients with OPA1 mutations

Patrick Yu‐Wai‐Man, Philip G. Griffiths, Gráinne S. Gorman et al. · Brain · 2010 · 437 citations · Full text

Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance

Gavin Hudson, Patrizia Amati‐Bonneau, Emma L. Blakely et al. · Brain · 2007 · 416 citations · Full text

Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background

Gavin Hudson, Valério Carelli, Liesbeth Spruijt et al. · The American Journal of Human Genetics · 2007 · 356 citations · Full text

Neurodegenerative Diseases, Clinical Expression, Ophthalmology +10

Identification of an X-Chromosomal Locus and Haplotype Modulating the Phenotype of a Mitochondrial DNA Disorder

Gavin Hudson, Sharon Keers, Patrick Yu Wai Man et al. · The American Journal of Human Genetics · 2005 · 191 citations · Full text

Biology, Dna, Mendelian Disorder +11