Lucy Granat

Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate

Rachel J. Hunt, Lucy Granat, Gregory S. McElroy et al. · The Journal of Cell Biology · 2019 · 51 citations · Full text

Mitochondrial retrograde signalling in neurological disease

Lucy Granat, Rachel J. Hunt, J.E. Bateman · Philosophical Transactions of the Royal Society B Biological Sciences · 2020 · 35 citations · Full text

Neurodegenerative Diseases, Mitophagy, Mitochondrial Function +12

Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency

Lucy Granat, Debbra Y. Knorr, Daniel C. Ranson et al. · PLoS Genetics · 2023 · 17 citations · Full text

Reductive Stress, Neurodegenerative Diseases, Mitochondrial Morphology Defects +14

Ras-ERK-ETS inhibition alleviates neuronal mitochondrial dysfunction by reprogramming mitochondrial retrograde signaling

Olivia F. Duncan, Lucy Granat, Ramya Ranganathan et al. · PLoS Genetics · 2018 · 16 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Genetics +18

Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

Annalisa Trecarichi, Natalie A. Duggett, Lucy Granat et al. · PLoS ONE · 2022 · 15 citations · Full text

Mitochondrial Dysfunction, Pain Medicine, Pathology +17