Iva Jelínková

Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes

Iva Gudernová, Iva Veselá, Lukáš Bálek et al. · Human Molecular Genetics · 2015 · 69 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage

Marcela Buchtová, Veronika Oralová, Anie Aklian et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2015 · 62 citations

Life Sciences, Cell Biology, Developmental Biology +14

An inactivating mutation in intestinal cell kinase,<i>ICK</i>, impairs hedgehog signalling and causes short rib-polydactyly syndrome

S. Paige Taylor, Michaela Kunova Bosakova, Miroslav Vařecha et al. · Human Molecular Genetics · 2016 · 59 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway

Olga Vondálová Blanářová, Iva Jelínková, Árpád Szöőr et al. · Carcinogenesis · 2010 · 40 citations · Full text

Life Sciences, Oncology, Pharmacology +17

DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism

Jiřina Hofmanová, Josef Slavík, Iva Jelínková et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2014 · 39 citations

Life Sciences, Cell Biology, Oncology +17