Jeffrey S. Nye

aph-1 and pen-2 Are Required for Notch Pathway Signaling, γ-Secretase Cleavage of βAPP, and Presenilin Protein Accumulation

Ross S. Francis, Garth McGrath, Jianhua Zhang et al. · Developmental Cell · 2002 · 794 citations · Full text

Protein Function, Signal Transduction, γ-Secretase Cleavage +9

Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain

Nicholas Gaiano, Jeffrey S. Nye, Gord Fishell · Neuron · 2000 · 721 citations · Full text

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

Seiji Hitoshi, Tania O. Alexson, Vincent Tropepe et al. · Genes & Development · 2002 · 682 citations · Full text

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

Raphael Kopan, Jeffrey S. Nye, Harold Weintraub · Development · 1994 · 476 citations

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

Raphael Kopan, Eric H. Schroeter, H Weintraub et al. · Proceedings of the National Academy of Sciences · 1996 · 472 citations · Full text

Extracellular Domain, Molecular Regulation, Cytoskeleton +19