Concepedia

Todd Machemer

TM

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Publications

26

Citations

1.5K

H-Index

20

Active since

1991

Affiliations

Ionis Pharmaceuticals (United States)(Current)

Slovenska Industrija Jekla (Slovenia)

University of California San Diego

Vrije Universiteit Amsterdam

Todd Machemer is an author at Ionis Pharmaceuticals (United States) specializing in medicine, adenovirus vectors, and oncology.

Publications per year

1991–2022

26

Publications

26

Cyclodextrin-Modified Polyethylenimine Polymers for Gene Delivery

Suzie H. Pun, Nathalie C. Bellocq, Aijie Liu et al. · Bioconjugate Chemistry · 2004 · 297 citations

, , +17

Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts

Sebastien A. Burel, Christopher E. Hart, Patrick Cauntay et al. · Nucleic Acids Research · 2015 · 200 citations · Full text

, , +16

Comprehensive Structure–Activity Relationship of Triantennary<i>N</i>-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

Thazha P. Prakash, Jinghua Yu, Michael T. Migawa et al. · Journal of Medicinal Chemistry · 2016 · 131 citations

, , +12

Adenovirus-mediatedp53 gene transfer suppresses growth of human glioblastoma cellsin vitro andin vivo

Helge Köck, Matthew P. Harris, Scott C. Anderson et al. · International Journal of Cancer · 1996 · 101 citations · Full text

, , +17

Ligand Conjugated Antisense Oligonucleotide for the Treatment of Transthyretin Amyloidosis: Preclinical and Phase 1 Data

Nicholas J. Viney, Shuling Guo, Brenda F. Baker et al. · ESC Heart Failure · 2020 · 91 citations · Full text

, , +14

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