Siddharthan Chandran

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

James Tollervey, Tomaž Curk, Boris Rogelj et al. · Nature Neuroscience · 2011 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

Nael H. Alami, Rebecca B. Smith, Mónica A. Carrasco et al. · Neuron · 2014 · 648 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Wouter van Rheenen, Aleksey Shatunov, Annelot M. Dekker et al. · Nature Genetics · 2016 · 628 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

Peter Connick, Madhan Kolappan, Charles Crawley et al. · The Lancet Neurology · 2012 · 606 citations · Full text

Life Sciences, Neurology, Neuroscience +15

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss et al. · Nature · 2022 · 514 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17