Karthik Krishnamurthy

Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death

Xinmei Wen, Wenzhi Tan, Thomas Westergard et al. · Neuron · 2014 · 545 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Medicine +8

Astrocytes expressing ALS‐linked mutant FUS induce motor neuron death through release of tumor necrosis factor‐alpha

Azadeh Kia, Kevin McAvoy, Karthik Krishnamurthy et al. · Glia · 2018 · 100 citations · Full text

Cell Death, Synaptic Signaling, Social Sciences +21

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity

J. Gavin Daigle, Karthik Krishnamurthy, Nandini Ramesh et al. · Acta Neuropathologica · 2016 · 71 citations · Full text

Systems Biology, Signal Transduction, Natural Sciences +12

Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ <scp>ALS</scp> / <scp>FTD</scp> is rescued by <scp>SV</scp> 2 replenishment

Brigid K. Jensen, Martin H Schuldi, Kevin McAvoy et al. · EMBO Molecular Medicine · 2020 · 52 citations · Full text

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

Ian Casci, Karthik Krishnamurthy, Sukhleen Kour et al. · Nature Communications · 2019 · 38 citations · Full text