Dharini Iyer

Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration

Johannes Bargehr, Lay Ping Ong, Maria Colzani et al. · Nature Biotechnology · 2019 · 207 citations · Full text

Tissue Engineering, Regenerative Medicine, Cardiac Muscle +15

Optimized inducible shRNA and CRISPR/Cas9 platforms for <i>in vitro</i> studies of human development using hPSCs

Alessandro Bertero, Matthias Pawlowski, Daniel Ortmann et al. · Development · 2016 · 96 citations · Full text

Engineering, In Vivo Gene Therapy, Genetics +22

TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells

Juyong Brian Kim, Milos Pjanic, Trieu Nguyen et al. · PLoS Genetics · 2017 · 73 citations · Full text

Immunology, Tcf21 Expression, Gene Characterization +20

Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk

Dharini Iyer, Quanyi Zhao, Robert Wirka et al. · PLoS Genetics · 2018 · 60 citations · Full text

Vascular Disease, Genetics, Gene Characterization +26

Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells

Dharini Iyer, Laure Gambardella, William G. Bernard et al. · Development · 2016 · 59 citations · Full text

Cell Culture, Cell Proliferation, Cell Growth +18