Karine Flem‐Karlsen

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

Joanna Poźniak, Dennis Pedri, Ewout Landeloos et al. · Cell · 2024 · 178 citations · Full text

Medicine, Cancer Biology, Oncology +17

Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors

Caroline E. Nunes‐Xavier, Karine Flem‐Karlsen, Christina Tekle et al. · Oncotarget · 2016 · 80 citations · Full text

Medicine, Cancer Biology, Oncology +13

Immunoregulatory protein B7‐H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells

Karine Flem‐Karlsen, Christina Tekle, Yvonne Andersson et al. · Pigment Cell & Melanoma Research · 2017 · 72 citations · Full text

Medicine, Oncology, Pharmacology +16

Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Algirdas Grevys, Rahel Frick, Simone Mester et al. · iScience · 2022 · 51 citations · Full text

Pharmacy, Biochemistry, Pharmacokinetics +17

IL-7R licenses a population of epigenetically poised memory CD8 ⁺ T cells with superior antitumor efficacy that are critical for melanoma memory

Goran Micevic, Andrew Daniels, Karine Flem‐Karlsen et al. · Proceedings of the National Academy of Sciences · 2023 · 44 citations · Full text

Life Sciences, Immunology, Oncology +17