Kazuo Ohtake

Screening of cationic compounds as an absorption enhancer for nasal drug delivery

Hideshi Natsume, Satoko Iwata, Kazuo Ohtake et al. · International Journal of Pharmaceutics · 1999 · 94 citations

Medicinal Chemistry, Pharmaceutical Science, Allergy +9

Poly-L-Arginine Predominantly Increases the Paracellular Permeability of Hydrophilic Macromolecules Across Rabbit Nasal Epithelium in Vitro

Kazuo Ohtake, Takuya Maeno, Hideo UEDA et al. · Pharmaceutical Research · 2003 · 73 citations

Poly-l-Arginine Enhances Paracellular Permeability via Serine/Threonine Phosphorylation of ZO-1 and Tyrosine Dephosphorylation of Occludin in Rabbit Nasal Epithelium

Kazuo Ohtake, Takuya Maeno, Hideo UEDA et al. · Pharmaceutical Research · 2003 · 67 citations

Molecular Physiology, Signal Transduction, Allergy +10

Improved nasal absorption of drugs using poly-l-arginine: effects of concentration and molecular weight of poly-l-arginine on the nasal absorption of fluorescein isothiocyanate–dextran in rats

Misao Miyamoto, Hideshi Natsume, Satoko Iwata et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2001 · 64 citations

Allergy, Pharmacological Study, Medicine +7

Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKAy mice

Kazuo Ohtake, Genya Nakano, Nobuyuki Ehara et al. · Nitric Oxide · 2014 · 60 citations

Insulin Resistance, Nutrition, Metabolic Syndrome +14