Junsaku Nagaoka

2-Alkynyl-8-aryl-9-methyladenines as Novel Adenosine Receptor Antagonists:  Their Synthesis and Structure−Activity Relationships toward Hepatic Glucose Production Induced via Agonism of the A_2BReceptor

Hitoshi Harada, Osamu Asano, Yorihisa Hoshino et al. · Journal of Medicinal Chemistry · 2000 · 111 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +13

Functional characterization of the adenosine receptor contributing to glycogenolysis and gluconeogenesis in rat hepatocytes

Nobuyuki Yasuda, Takashi Inoue, Tatsuo Horizoe et al. · European Journal of Pharmacology · 2003 · 67 citations

Cell Physiology, Molecular Physiology, Signal Transduction +14

2-Alkynyl-8-aryladenines possessing an amide moiety: their synthesis and structure–activity relationships of effects on hepatic glucose production induced via agonism of the A2B adenosine receptor

Hitoshi Harada, Osamu Asano, Tsutomu Kawata et al. · Bioorganic & Medicinal Chemistry · 2001 · 31 citations

Molecular Pharmacology, Aldo-keto Reductase, Biochemistry +6

Inhibitory effects of the novel platelet activating factor receptor antagonist, 1-ethyl-2-[N-(2-methoxy)benzoyl-N-[(2R)-2-methoxy-3-(4- octadecylcarbamoyloxy) piperidinocarbonyloxypropyloxy]carbonyl] aminomethyl-pyridinium chloride, in several experimentally induced shock models.

Junsaku Nagaoka, K Harada, Akufumi Kimura et al. · PubMed · 1991 · 24 citations

Novel Platelet, Pharmacotherapy, Experimental Pharmacology +19