Lauren M. Gutgesell

Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer

Rui Xiong, Jiong Zhao, Lauren M. Gutgesell et al. · Journal of Medicinal Chemistry · 2017 · 78 citations · Full text

Breast Oncology, Chemoprevention Strategy, Er+ Cell Lines +20

Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer

Rui Xiong, Hitisha Patel, Lauren M. Gutgesell et al. · Journal of Medicinal Chemistry · 2015 · 60 citations · Full text

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

Kaitlyn J. Andreano, Suzanne E. Wardell, Jennifer G. Baker et al. · Breast Cancer Research and Treatment · 2020 · 46 citations · Full text

Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

Yunlong Lu, Lauren M. Gutgesell, Rui Xiong et al. · Journal of Medicinal Chemistry · 2019 · 39 citations · Full text

Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib

Yangfeng Li, Jiong Zhao, Lauren M. Gutgesell et al. · Journal of Medicinal Chemistry · 2020 · 33 citations · Full text