Kaitlyn J. Andreano

The Signaling Pathways Project, an integrated ‘omics knowledgebase for mammalian cellular signaling pathways

Scott A. Ochsner, David Abraham, Kirt Martin et al. · Scientific Data · 2019 · 132 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer

John D. Norris, Stephanie J. Ellison, Jennifer G. Baker et al. · Journal of Clinical Investigation · 2017 · 59 citations · Full text

Medicine, Oncology, Pharmacology +17

Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy

Suzanne E. Wardell, Alexander P. Yllanes, Christina Chao et al. · Breast Cancer Research and Treatment · 2019 · 55 citations · Full text

Medicine, Oncology, Pharmacology +17

The Dysregulated Pharmacology of Clinically Relevant <i>ESR1</i> Mutants is Normalized by Ligand-activated WT Receptor

Kaitlyn J. Andreano, Jennifer G. Baker, Sunghee Park et al. · Molecular Cancer Therapeutics · 2020 · 50 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

Kaitlyn J. Andreano, Suzanne E. Wardell, Jennifer G. Baker et al. · Breast Cancer Research and Treatment · 2020 · 46 citations · Full text

Medicine, Oncology, Pharmacology +17