Emma L. James

Senescent Human Fibroblasts Show Increased Glycolysis and Redox Homeostasis with Extracellular Metabolomes That Overlap with Those of Irreparable DNA Damage, Aging, and Disease

Emma L. James, Ryan D. Michalek, Gayani Pitiyage et al. · Journal of Proteome Research · 2015 · 237 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Efficacy of FLU-v, a broad-spectrum influenza vaccine, in a randomized phase IIb human influenza challenge study

Olga Pleguezuelos, Emma L. James, Ana M. Fernández et al. · npj Vaccines · 2020 · 82 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Areca nut alkaloids induce irreparable <scp>DNA</scp> damage and senescence in fibroblasts and may create a favourable environment for tumour progression

Ambreen Rehman, Sitara Ali, Mohid Abrar Lone et al. · Journal of Oral Pathology and Medicine · 2015 · 62 citations

Medicine, Oncology, Pharmacology +17

Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial

Jessica E. Manning, Fabiano Oliveira, Iliano V. Coutinho-Abreu et al. · The Lancet · 2020 · 59 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +12

Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism

Emma L. James, James A. E. Lane, Ryan D. Michalek et al. · Scientific Reports · 2016 · 40 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15