Flora Huang

Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

Steven M. Lewis, Xiufeng Wu, Anna Pustilnik et al. · Nature Biotechnology · 2014 · 237 citations

Immunocytochemical Technique, Engineering, Immunology +13

Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy

Bruce G. Szczepankiewicz, Gang Liu, Philip J. Hajduk et al. · Journal of the American Chemical Society · 2003 · 226 citations · Full text

Type Ii Diabetes, Drug Target, Biochemistry +15

Stability engineering of scFvs for the development of bispecific and multivalent antibodies

Brian Miller, Stephen J. Demarest, Alexey A. Lugovskoy et al. · Protein Engineering Design and Selection · 2010 · 127 citations

Engineering, Immunology, Molecular Biology +17

Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTβR

Jennifer S. Michaelson, Stephen J. Demarest, Brian Miller et al. · mAbs · 2009 · 115 citations · Full text

Statins to prevent early cardiac dysfunction in cancer patients at increased cardiotoxicity risk receiving anthracyclines

Paaladinesh Thavendiranathan, Christian Houbois, Thomas H. Marwick et al. · European Heart Journal - Cardiovascular Pharmacotherapy · 2023 · 91 citations · Full text