Pamela Hill

Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy

Brian Sherer, Kenneth G. Hull, Oluyinka Green et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 119 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Medicine +10

Optimization of Pyrrolamide Topoisomerase II Inhibitors Toward Identification of an Antibacterial Clinical Candidate (AZD5099)

Gregory S. Basarab, Pamela Hill, C. Edwin Garner et al. · Journal of Medicinal Chemistry · 2014 · 78 citations · Full text

Resistance Frequency, Medicinal Chemistry, Bioorganic Chemistry +15

Selective Inhibitors of Bacterial t-RNA-(N¹G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain

Pamela Hill, Ayome Abibi, Robert Albert et al. · Journal of Medicinal Chemistry · 2013 · 54 citations

Bioorganic Chemistry, Engineering, X-ray Cocrystal Structures +20

Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines

Bolin Geng, Gregory S. Basarab, Janelle Comita-Prevoir et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 49 citations · Full text

Medicine, Glutamate Racemase, Mechanism Of Action +10

DrugnomeAI is an ensemble machine-learning framework for predicting druggability of candidate drug targets

Arwa Bin Raies, Ewa Tulodziecka, James Stainer et al. · Communications Biology · 2022 · 49 citations · Full text