Marie Wetzel

New Drug-Like Hydroxyphenylnaphthol Steroidomimetics As Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Estrogen-Dependent Diseases

Sandrine Marchais‐Oberwinkler, Marie Wetzel, Erika Ziegler et al. · Journal of Medicinal Chemistry · 2010 · 53 citations · Full text

Introduction of an Electron Withdrawing Group on the Hydroxyphenylnaphthol Scaffold Improves the Potency of 17β-Hydroxysteroid Dehydrogenase Type 2 (17β-HSD2) Inhibitors

Marie Wetzel, Sandrine Marchais‐Oberwinkler, Enrico Perspicace et al. · Journal of Medicinal Chemistry · 2011 · 46 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Osteoporosis +18

17β-HSD2 inhibitors for the treatment of osteoporosis: Identification of a promising scaffold

Marie Wetzel, Sandrine Marchais‐Oberwinkler, Rolf W. Hartmann · Bioorganic & Medicinal Chemistry · 2010 · 43 citations · Full text

Bone Disease, Molecular Pharmacology, Promising Scaffold +8

Discovery of a new class of bicyclic substituted hydroxyphenylmethanones as 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors for the treatment of osteoporosis

Marie Wetzel, Emanuele M. Gargano, Stefan Hinsberger et al. · European Journal of Medicinal Chemistry · 2011 · 25 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis

Sandrine Marchais‐Oberwinkler, Kuiying Xu, Marie Wetzel et al. · Journal of Medicinal Chemistry · 2012 · 24 citations · Full text