Bas van der Woning

Structural basis of latent TGF-β1 presentation and activation by GARP on human regulatory T cells

Stéphanie Liénart, Romain Merceron, Christophe Vanderaa et al. · Science · 2018 · 152 citations

Life Sciences, Immunology, Molecular Biology +13

Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo

Julia Cuende, Stéphanie Liénart, Olivier Dedobbeleer et al. · Science Translational Medicine · 2015 · 144 citations · Full text

Life Sciences, Immunology, Oncology +15

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer

Grégoire de Streel, Charlotte Bertrand, Nicolas Chalon et al. · Nature Communications · 2020 · 139 citations · Full text

Medicine, Immunology, Oncology +17

Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions

Vladimir Bobkov, Aurélien Zarca, Anneleen Van Hout et al. · Biochemical Pharmacology · 2018 · 72 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA

Olivier Dedobbeleer, Julie Stockis, Bas van der Woning et al. · The Journal of Immunology · 2017 · 60 citations · Full text

Life Sciences, Immunology, Molecular Biology +14