Anneleen Van Hout

Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions

Vladimir Bobkov, Aurélien Zarca, Anneleen Van Hout et al. · Biochemical Pharmacology · 2018 · 69 citations · Full text

CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry

Anneleen Van Hout, A. Klarenbeek, Vladimir Bobkov et al. · Biochemical Pharmacology · 2018 · 56 citations · Full text

Hiv Entry, Human Retrovirus, Immunology +3

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors

Anneleen Van Hout, Thomas D’huys, Merel Oeyen et al. · PLoS ONE · 2017 · 49 citations · Full text

Drug Target, Chemokine Biology, Immunology +21

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

Geert Schoofs, Anneleen Van Hout, Thomas D’huys et al. · Journal of Visualized Experiments · 2018 · 22 citations · Full text

Pharmacological Targeting, Immunocytochemical Technique, Cxcr4-targeting Compounds +15

Monocytes from patients with Primary Ciliary Dyskinesia show enhanced inflammatory properties and produce higher levels of pro-inflammatory cytokines

Maaike Cockx, Mieke Gouwy, Pieter Ruytinx et al. · Scientific Reports · 2017 · 17 citations · Full text

Chronic Inflammatory Diseases, Chemokine Biology, Inflammatory Lung Disease +23