Gregory W. Kauffman

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Antonia F. Stepan, Chakrapani Subramanyam, Ivan Efremov et al. · Journal of Medicinal Chemistry · 2012 · 446 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Physicochemical Features of the hERG Channel Drug Binding Site

David Fernández, Azad Ghanta, Gregory W. Kauffman et al. · Journal of Biological Chemistry · 2004 · 265 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

QSAR and <i>k</i>-Nearest Neighbor Classification Analysis of Selective Cyclooxygenase-2 Inhibitors Using Topologically-Based Numerical Descriptors

Gregory W. Kauffman, Peter C. Jurs · Journal of Chemical Information and Computer Sciences · 2001 · 126 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Prediction of Surface Tension, Viscosity, and Thermal Conductivity for Common Organic Solvents Using Quantitative Structure−Property Relationships

Gregory W. Kauffman, Peter C. Jurs · Journal of Chemical Information and Computer Sciences · 2001 · 125 citations

Natural Sciences, Chemical Engineering, Chemistry +17

Quantitative Assessment of the Impact of Fluorine Substitution on P-Glycoprotein (P-gp) Mediated Efflux, Permeability, Lipophilicity, and Metabolic Stability

Martin Pettersson, Xinjun Hou, Max Kühn et al. · Journal of Medicinal Chemistry · 2016 · 117 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14