Fieke W. Hoff

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

Geethu Emily Thomas, Grace Egan, Laura García‐Prat et al. · Nature Cell Biology · 2022 · 82 citations · Full text

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

Natalia Baran, Alessia Lodi, Yogesh Dhungana et al. · Nature Communications · 2022 · 57 citations · Full text

The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability

Sara Mirali, Aaron Botham, Véronique Voisin et al. · Science Translational Medicine · 2020 · 44 citations · Full text

Immunology, Molecular Biology, Cell Death +16

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit

Hee-Don Chae, Ritika Dutta, Bruce Tiu et al. · Oncotarget · 2020 · 31 citations · Full text

Mixed-phenotype Acute Leukemia, Acute Leukemia Cells, Apoptosis +16

Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia

Anneke D. van Dijk, Fieke W. Hoff, Yongchang Qiu et al. · Clinical Epigenetics · 2021 · 29 citations · Full text