Isabelle Walter

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling

Nicole A. Kratochwil, Christophe Meille, Stephen Fowler et al. · The AAPS Journal · 2017 · 109 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Potential inhibitory effects of formulation ingredients on intestinal cytochrome P450

Richard J. Mountfield, Sandrine Senepin, Michael Schleimer et al. · International Journal of Pharmaceutics · 2000 · 102 citations

Medicine, Pharmacokinetics, Pharmacology +16

<i>In vitro</i> investigation on the impact of the surface‐active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam

Roberto Carlos Bravo González, Jörg Huwyler, Franziska Boess et al. · Biopharmaceutics & Drug Disposition · 2004 · 88 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Calibration of In Vitro Multidrug Resistance Protein 1 Substrate and Inhibition Assays as a Basis to Support the Prediction of Clinically Relevant Interactions In Vivo

Agnès Poirier, Anne‐Christine Cascais, Urs Bader et al. · Drug Metabolism and Disposition · 2014 · 47 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

The Need for Human Breast Cancer Resistance Protein Substrate and Inhibition Evaluation in Drug Discovery and Development: Why, When, and How?

Agnès Poirier, Renée Portmann, Anne‐Christine Cascais et al. · Drug Metabolism and Disposition · 2014 · 46 citations

Medicine, Pharmacokinetics, Pharmacology +17