Padma Malyala

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

Kiran Musunuru, Alexandra C. Chadwick, Taiji Mizoguchi et al. · Nature · 2021 · 768 citations

Life Sciences, Genetics, Molecular Biology +12

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

Fiona A. Sharp, Darren Ruane, Benjamin Claass et al. · Proceedings of the National Academy of Sciences · 2009 · 536 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Rational design of small molecules as vaccine adjuvants

Tom Wu, Manmohan Singh, Andrew T. Miller et al. · Science Translational Medicine · 2014 · 176 citations

Life Sciences, Immunology, Medicinal Chemistry +17

GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy

Lisa N. Kasiewicz, Souvik Biswas, Aaron Beach et al. · Nature Communications · 2023 · 145 citations · Full text

Pharmacy, Biotechnology, Pharmaceutics +17

Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization

Joseph R. Francica, Zizhang Sheng, Zhenhai Zhang et al. · Nature Communications · 2015 · 93 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17