G Pomatico

Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor.

Fortunato Ciardiello, R. Caputo, Roberto Bianco et al. · PubMed · 2000 · 938 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells.

Fortunato Ciardiello, Roberto Bianco, V. Damiano et al. · PubMed · 2000 · 380 citations

Medicine, Oncology, Pharmacology +17

Cooperative Inhibition of Renal Cancer Growth by Anti-Epidermal Growth Factor Receptor Antibody and Protein Kinase A Antisense Oligonucleotide

Fortunato Ciardiello, Rosa Caputo, Roberto Bianco et al. · JNCI Journal of the National Cancer Institute · 1998 · 77 citations · Full text

Medicine, Oncology, Pharmacology +17

Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting protein kinase A in combination with docetaxel and anti-epidermal growth factor-receptor antibody on human breast cancer cell growth.

Giampaolo Tortora, R. Caputo, G Pomatico et al. · PubMed · 1999 · 61 citations

Medicine, Oncology, Pharmacology +16

Resistance to taxanes is induced by c-erbB-2 overexpression in human MCF-10A mammary epithelial cells and is blocked by combined treatment with an antisense oligonucleotide targeting type I protein kinase A

Fortunato Ciardiello, Rosa Caputo, G Pomatico et al. · International Journal of Cancer · 2000 · 59 citations · Full text

Medicine, Oncology, Pharmacology +17