A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

David Ahern, Zhichao Ai, Mark Ainsworth, +202

Cell

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Yanchun Peng, Suet Ling Felce, Danning Dong, +62

Nature Immunology

Identification of HIV transmitting CD11c+ human epidermal dendritic cells

Kirstie M. Bertram, Rachel A. Botting, Heeva Baharlou, +26

Nature Communications

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8 ⁺ T cell clone size and cytotoxicity

Robert Watson, Orion Tong, Rosalin Cooper, +8

Science Immunology

IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance and diversity of intra-tumoral stem-like T cells

Julie M. Mazet, Jagdish N. Mahale, Orion Tong, +9

Nature Communications

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

Chelsea Taylor, Robert Watson, Orion Tong, +22

Nature Medicine

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

David Ahern, Zhichao Ai, Mark Ainsworth, +199

Covid-19 Defines HallmarksViral DiagnosticsImmunologyPathologyMultiomics +22

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19

Christos P. Kotanidis, Cheng Xie, Donna Maria Alexander, +313

The Lancet Digital Health

Vascular DiseaseRoutine Ct AngiogramsMedical ImagingMedicineVascular Inflammation +10

Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity

James J. Gilchrist, Seiko Makino, Vivek Naranbhai, +15

Nature Communications

InflammationImmunogeneticsHealthy EuropeansAllergyAutoimmune Disease +13

Plasmacytoid dendritic cells have divergent effects on HIV infection of initial target cells and induce a pro-retention phenotype

Orion Tong, Gabriel Duette, Thomas R. O’Neil, +15

PLoS Pathogens

ImmunologyCcr5 ExpressionImmunotherapyPdcs Impacted InfectionHuman Retrovirus +14