Theo Battista

Identification of chalcone-based antileishmanial agents targeting trypanothione reductase

Margherita Ortalli, Andrea Ilari, Gianni Colotti et al. · European Journal of Medicinal Chemistry · 2018 · 73 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +9

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases

Ilaria Genovese, Flavia Giamogante, Lucia Barazzuol et al. · Cell Death and Disease · 2020 · 57 citations · Full text

Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors

Andrea Ilari, Ilaria Genovese, Fabiana Fiorillo et al. · Molecular Pharmaceutics · 2018 · 31 citations

Gene Conservation, Bioorganic Chemistry, Antiparasitic Agent +19

Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism

Gianni Colotti, Francesco Saccoliti, Marina Gramiccia et al. · Amino Acids · 2019 · 23 citations

Medicinal Chemistry, Bioorganic Chemistry, Structure-guided Approach +12

The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket

Chiara Ciaccio, Lorenzo Tognaccini, Theo Battista et al. · Journal of Inorganic Biochemistry · 2017 · 22 citations · Full text

Molecular Pharmacology, Molecular Physiology, Ligand Access +13