Ilaria Genovese

Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening

Lorenzo Turcano, Esther Torrente, Antonino Missineo et al. · PLoS neglected tropical diseases · 2018 · 62 citations · Full text

Hit Identification, Biochemistry, African Trypanosomiasis +13

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases

Ilaria Genovese, Flavia Giamogante, Lucia Barazzuol et al. · Cell Death and Disease · 2020 · 57 citations · Full text

Structural basis of Sorcin-mediated calcium-dependent signal transduction

Andrea Ilari, Annarita Fiorillo, Elena Poser et al. · Scientific Reports · 2015 · 54 citations · Full text

Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells

Ilaria Genovese, Annarita Fiorillo, Andrea Ilari et al. · Cell Death and Disease · 2017 · 49 citations · Full text

Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors

Andrea Ilari, Ilaria Genovese, Fabiana Fiorillo et al. · Molecular Pharmaceutics · 2018 · 31 citations

Gene Conservation, Bioorganic Chemistry, Antiparasitic Agent +19