A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress

Paco Pino, Reto Caldelari, Budhaditya Mukherjee, +9

Science

Protein SecretionAntiparasitic AgentMedicinePathogenesisImmunology +13

An Apicomplexan Actin-Binding Protein Serves as a Connector and Lipid Sensor to Coordinate Motility and Invasion

Damien Jacot, Nicolò Tosetti, Isa Pires, +7

Cell Host & Microbe

Proteinlipid InteractionProtein FunctionSignal TransductionLipid SensorNatural Sciences +11

Crystal Structure of Triosephosphate Isomerase Complexed with 2-Phosphoglycolate at 0.83-Å Resolution

Inari Kursula, Rik K. Wierenga

Journal of Biological Chemistry

Structural Differences Explain Diverse Functions of Plasmodium Actins

Juha Vahokoski, Saligram Prabhakar Bhargav, Ambroise Desfosses, +9

PLoS Pathogens

Protein AssemblyMalariaMolecular BiologyCytoskeletonMalaria Parasite +15

Structural and Functional Characterization of Human Peripheral Nervous System Myelin Protein P2

Viivi Majava, Eugenia Polverini, Alberto Mazzini, +7

PLoS ONE

Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability

Sabrina Pospich, Esa‐Pekka Kumpula, Julian von der Ecken, +3

Proceedings of the National Academy of Sciences

High-resolution Structural Analysis of Mammalian Profilin 2a Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of mDia1 and the Proline-rich Domain of VASP

Petri Kursula, Inari Kursula, Marzia Massimi, +5

Journal of Molecular Biology

Mammalian Profilin 2AProtein FunctionMolecular PhysiologyFormin Homology 1Protein Assembly +10

Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium falciparum

Inari Kursula, Petri Kursula, Markus Ganter, +3

Structure

BiologyParasitic ProtozoaMedicineNatural SciencesMalaria +9

A unique profilin-actin interface is important for malaria parasite motility

Catherine Moreau, Saligram Prabhakar Bhargav, Hirdesh Kumar, +9

PLoS Pathogens

Protein AssemblyAntiparasitic AgentMalariaMolecular BiologyCytoskeleton +14

Structure of <i>Toxoplasma gondii</i> coronin, an actin‐binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress

Julien Salamun, Juha P. Kallio, Wassim Daher, +2

The FASEB Journal